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Description

MA1-90420, Invitrogen

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Uses What is Lidocaine HCl used for

Macitentan (10 mg) Class: Endothelin Receptor Antagonist Used for: Pulmonary Arterial Hypertension (PAH) Metabolism: Mainly by CYP3A4 enzyme Major DrugDrug Interactions Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir, clarithromycin) Decrease metabolism Increase Macitentan level _ Risk of liver toxicity, headache, edema Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin, phenobarbital, St